3-(3-pyridinyl)-1H-pyrazole-5-carboxylic acid hydrochloride - Names and Identifiers
3-(3-pyridinyl)-1H-pyrazole-5-carboxylic acid hydrochloride - Physico-chemical Properties
Molecular Formula | C9H8ClN3O2
|
Molar Mass | 225.63172 |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD09997651 |
3-(3-pyridinyl)-1H-pyrazole-5-carboxylic acid hydrochloride - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Hazard Class | IRRITANT |
3-(3-pyridinyl)-1H-pyrazole-5-carboxylic acid hydrochloride - Introduction
acidhydrochloride is an organic compound with the chemical formula C10H8N4O2 · HCl. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline solid
-Melting point: 176-181°C
-Molecular weight: 258.65g/mol
-Solubility: Soluble in water and alcohol solvents
Use:
-acidhydrochloride is an important organic synthesis intermediate, commonly used in the synthesis of compounds containing a pyrazole ring structure
-It is widely used in the field of medicine, as a precursor of anti-inflammatory, antibacterial, anti-tumor and antiviral drugs
Preparation Method:
The preparation method of the acidhydrochloride can be carried out by the following steps:
1.3-aminopyridine and appropriate amount of pyrazole carboxylic acid are reacted in an appropriate solvent to generate 5-(pyridin-3-yl)-1H-pyrazole -3-carboxylic acid
2. add hydrochloric acid to the generated carboxylic acid to obtain acidhydrochloride
3. Finally, the reaction mixture was filtered to remove the solid and purified by crystallization to obtain the target product
Safety Information:
-the lack of detailed safety information reported acidhydrochloride, so the use of the process should follow the safety procedures of the chemical laboratory, including wearing appropriate personal protective equipment and eye, skin, respiratory system equipment
-When handling the compound, avoid direct contact with the skin and inhalation of dust or gas
-Appropriate ventilation measures should be taken when storing and handling the compound
-If necessary, it is recommended to refer to reliable chemical literature and safety data forms for more detailed safety information before conducting experiments.
Last Update:2024-04-09 21:00:56